| Authors |
Gupta P, Doherty L, Temprosa M, Pop-Busui R, Gadde KM, Singh P, Owora AH,
Wessells H, Sarma AV,
|
| Submitted By |
Submitted Externally on 4/25/2024 |
| Status |
Published |
| Journal |
Neurourology and urodynamics, REFERENCES |
| Year |
2024 |
| Date Published |
4/1/2024 |
| Volume : Pages |
43 : 977 - 990 |
| PubMed Reference |
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| Abstract |
To determine the burden and identify correlates of female sexual dysfunction
(FSD) among women with prediabetes (PreD) and type 2 diabetes (T2D) enrolled in
the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS)., The DPPOS visit
included the Female Sexual Function Index (FSFI) to determine sexual function.
Of 1464 participants, 1320 (90%) completed the (FSFI) and 426 were sexually
active. A backward selection multivariable logistic regression model estimated
the odds of FSD for sociodemographic, clinical, and diabetes-related
covariates., One hundred and eighty-five聽(43%) had a score of =26.55 and met the
criteria for FSD. After adjustment for DPP treatment and age, urinary
incontinence (UI) (odds ratio [OR]?=?1.91, 95% confidence interval
[CI]?=?1.15-3.17) and hysterectomy (OR?=?1.89, 95%聽CI?=?1.01-3.53) were
associated with increased odds of FSD. Increased body mass index was protective
for FSD (OR?=?0.93 per kg/m2, 95%聽CI?=?0.89-0.96). Michigan Neuropathy Screening
Instrument-based peripheral neuropathy (mean卤SD scores 1.1卤1.3 vs. 0.9卤1.1,
p?(mean?卤?SD heart rate levels 64.3?卤?6.8 vs. 65.6?卤?10.2, p?=?0.008) were
associated with FSD. There were no differences in diabetes rates between women
who did (66.5%) and did not (66%) have (p?=?0.7)., FSD is prevalent in women
with PreD and T2D. Our findings suggest that FSD is associated with neuropathic
complications commonly observed in PreD and T2D.
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