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MRI biomarkers for evaluation of treatment efficacy in preclinical diabetic
retinopathy.
Authors Berkowitz BA, Bissig D, Dutczak O, Corbett S, North R, Roberts R
Submitted By Submitted Externally on 5/2/2014
Status Published
Journal Expert opinion on medical diagnostics
Year 2013
Date Published 7/1/2013
Volume : Pages 7 : 393 - 403
PubMed Reference
Abstract One sober consequence of the current epidemic of diabetes mellitus is that an
increasing number of people world-wide will partially or completely lose their
sight to diabetic retinopathy. Clinically, the sight-threatening complications
of diabetes are diagnosed and treated based on visible retinal lesions (e.g.,
dot-blot hemorrhages or retinal neovascularization). However, such anatomical
microvascular lesions are slow to respond with treatment. Thus, there remains an
urgent need for imaging biomarkers that are abnormal before retinal lesions are
visibly apparent and are responsive to treatment.


Investigators with authorship
NameInstitution
Bruce BerkowitzWayne State University

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