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Publication

A Plumbing Solution for Stem Cell-Derived Kidneys.

Authors 脫 hAinmhire E, Humphreys BD Submitted By Benjamin Humphreys on 4/15/2016 Status Published Journal Transplantation Year 2016 Date Published Volume : Pages 100 : 3 - 4 PubMed Reference Abstract Over the last decade, the notion that stem cell biology can be harnessed to generate transplantable human kidneys has received much attention, even if progress has been slow.1 In the last 2 years, however, 2 independent approaches toward generating transplantable kidneys have demonstrated major progress. In 1 strategy, pluripotent human cells have been shown to possess the capacity to differentiate into nephron-like structures in a dish鈥攈undreds of them, in fact.2 These in vitro kidney organoids self-assemble once the proper ratio of progenitor cell populations is generated, and evidence suggests that they can respond to injurious stimuli much as mammalian nephrons do.

Investigators with authorship
Name Institution Benjamin Humphreys Washington University in St Louis

Complications
All ComplicationsBioinformatics BoneCardiomyopathy CardiovascularGastro-Intestinal (GI) NephropathyNeuropathy & Neurocognition Pediatric Endocrinology Retinopathy UropathyWound Healing