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Publication

Evidence for diffuse central retinal edema in vivo in diabetic male sprague dawley rats.

Authors Berkowitz BA, Bissig D, Ye Y, Valsadia P, Kern TS, Roberts R Submitted By Tim Kern on 2/22/2012 Status Published Journal PLoS ONE Year 2012 Date Published 4/1/2012 Volume : Pages 7 : e29619 PubMed Reference Abstract Investigations into the mechanism of diffuse retinal edema in diabetic subjects have been limited by a lack of animal models and techniques that co-localized retinal thickness and hydration in vivo. In this study we test the hypothesis that a previously reported supernormal central retinal thickness on MRI measured in experimental diabetic retinopathy in vivo represents a persistent and diffuse edema.

Investigators with authorship
Name Institution Bruce Berkowitz Wayne State University Tim Kern Case Western Reserve

Complications
All ComplicationsBioinformatics BoneCardiomyopathy CardiovascularGastro-Intestinal (GI) NephropathyNeuropathy & Neurocognition Pediatric Endocrinology Retinopathy UropathyWound Healing