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Murine-HumanTranscriptomic Comparisons in Diabetic Nephropathy and Neuropathy

Summary

Data Summary

Applicant	Kretzler, Matthias
E-Mail Address	kretzler@umich.edu
Project Title	Murine-HumanTranscriptomic Comparisons in Diabetic Nephropathy and Neuropathy
CBU ID	10MCG106
External SubContract ID	20497-19
Diabetic Complication	Nephropathy
Funding Program Group	Pilot & Feasibility [PF2008]
Abstract	Comparison of genome-wide transcriptional profiles obtained from human and murine diabetic nephropathy (DN) and polyneuropathy (DPN) should allow identification of diabetic endorgan damage mechanisms that are conserved between mice and humans as well as those that are important in humans but whose absence in mice impairs development of full-blown DN or DPN. Targeting these pathways should greatly facilitate translation of findings from animal models to human disease and the development of improved murine models of DN and DPN.
Application PDF	Application Research Plan
Status	Contract Executed
Key Personnel
Salary Total Costs	26307
Supply Total Costs	39482
Equipment Total Costs	0
Travel/Other Total Costs	0
Direct Costs	65789
Indirect Costs Proposed	34211
Total Costs Proposed	100000
Total Costs Approved	100000
Start Date	8/1/2008
End Date	7/31/2009
IFO Name	Maxwell, Teri
IFO E-Mail Address	tmax@umich.edu
IACUC/IRB No.	A3114-01
IACUC/IRB Institution	University of Michigan
Entity ID No.
Report Request Date	9/28/2009
T1D	NO

Type	Count
Invoices	0
Progress Reports	1

Data Submission

Author	Complete Date	Report
Kretzler, Matthias	9/2/2009	View Progress Report Document

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